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Dima Biotech

FLP100102

Human PROKR1 full length protein-synthetic nanodisc

Human PROKR1 full length protein-synthetic nanodisc

Size
PRODUCT DATA
TARGET

SYNONYMS

GPR73; GPR73a; PK-R1; PKR1; ZAQ
DESCRIPTION

Human PROKR1 full length protein-synthetic nanodisc
DELIVERY

3-4 weeks
UNIPROT ID

Q8TCW9
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, GPCR, Transmembrane
PROTEIN PATHWAYS
MOLECULAR WEIGHT

The human full length PROKR1 protein has a MW of 44.6 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
USAGE

Research use only
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