TARGET | |
---|---|
SYNONYMS |
hTDAG8; TDAG8 |
DESCRIPTION |
Human GPR65 full length protein-synthetic nanodisc |
DELIVERY |
3-4 weeks |
UNIPROT ID |
Q8IYL9 |
EXPRESSION HOST |
HEK293 |
PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
PROTEIN PATHWAYS | |
MOLECULAR WEIGHT |
The human full length GPR65 protein has a MW of 39.3 kDa |
FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).[UniProtKB/Swiss-Prot Function] |
USAGE |
Research use only |
SKU(재고 관리 코드):FLP100103