TARGET | |
---|---|
SYNONYMS |
BFPP; BPPR; GPR56; TM7LN4; TM7XN1 |
DESCRIPTION |
Human ADGRG1 full length protein-synthetic nanodisc |
DELIVERY |
In Stock |
UNIPROT ID |
Q9Y653 |
EXPRESSION HOST |
HEK293 |
PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
PROTEIN PATHWAYS |
N.A. |
MOLECULAR WEIGHT |
The human full length ADGRG1 protein has a MW of 77.7 kDa |
FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
A member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. |
USAGE |
Research use only |
SKU(재고 관리 코드):FLP100104
Human ADGRG1 full length protein-synthetic nanodisc
Human ADGRG1 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag ADGRG1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with ADGRG1-Nanodisc is 1.419ng/ml.
Figure2. Human ADGRG1-Nanodisc, Flag Tag on SDS-PAGE