| TARGET | |
|---|---|
| SYNONYMS |
CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28 |
| DESCRIPTION |
Human CX3CR1 full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
P49238 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
| PROTEIN PATHWAYS |
Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| MOLECULAR WEIGHT |
The human full length CX3CR1 protein has a MW of 40.4 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100115
Human CX3CR1 full length protein-synthetic nanodisc
Human CX3CR1 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag CX3CR1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CX3CR1-Nanodisc is 2.796ng/ml.
Figure2. Human CX3CR1-Nanodisc, Flag Tag on SDS-PAGE
