TARGET | |
---|---|
SYNONYMS |
G2A |
DESCRIPTION |
Human GPR132 full length protein-synthetic nanodisc |
DELIVERY |
3-4 weeks |
UNIPROT ID |
Q9UNW8 |
EXPRESSION HOST |
HEK293 |
PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
PROTEIN PATHWAYS | |
MOLECULAR WEIGHT |
The human full length GPR132 protein has a MW of 42.5 kDa |
FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
USAGE |
Research use only |
SKU(재고 관리 코드):FLP100116