| TARGET | |
|---|---|
| SYNONYMS |
CCXCR1; GPR5 |
| DESCRIPTION |
Human XCR1 full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
P46094 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
| PROTEIN PATHWAYS |
Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| MOLECULAR WEIGHT |
The human full length XCR1 protein has a MW of 38.5 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):FLP100120
Human XCR1 full length protein-synthetic nanodisc
Human XCR1 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag XCR1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with XCR1-Nanodisc is 2.130ng/ml.
Figure2. Human XCR1-Nanodisc, Flag Tag on SDS-PAGE
