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Dima Biotech

FLP100123

Human BDKRB2 full length protein-synthetic nanodisc

Human BDKRB2 full length protein-synthetic nanodisc

Size
PRODUCT DATA
TARGET

SYNONYMS

B2R; BK-2; BK2; BKR2; BRB2
DESCRIPTION

Human BDKRB2 full length protein-synthetic nanodisc
DELIVERY

3-4 weeks
UNIPROT ID

P30411
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, GPCR, Transmembrane
PROTEIN PATHWAYS

Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
MOLECULAR WEIGHT

The human full length BDKRB2 protein has a MW of 44.5 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]
USAGE

Research use only
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