| TARGET | |
|---|---|
| SYNONYMS |
B2R; BK-2; BK2; BKR2; BRB2 |
| DESCRIPTION |
Human BDKRB2 full length protein-synthetic nanodisc |
| DELIVERY |
3-4 weeks |
| UNIPROT ID |
P30411 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
| PROTEIN PATHWAYS |
Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton |
| MOLECULAR WEIGHT |
The human full length BDKRB2 protein has a MW of 44.5 kDa |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020] |
| USAGE |
Research use only |
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Dima Biotech
SKU(재고 관리 코드):FLP100123
Human BDKRB2 full length protein-synthetic nanodisc
Human BDKRB2 full length protein-synthetic nanodisc
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