TARGET | |
---|---|
SYNONYMS |
NTR |
DESCRIPTION |
Human NTSR1 full length protein-synthetic nanodisc |
DELIVERY |
In Stock |
UNIPROT ID |
P30989 |
EXPRESSION HOST |
HEK293 |
PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
PROTEIN PATHWAYS |
Calcium signaling pathway, Neuroactive ligand-receptor interaction |
MOLECULAR WEIGHT |
The human full length NTSR1 protein has a MW of 46.1 kDa |
FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. |
USAGE |
Research use only |
SKU(재고 관리 코드):FLP100131
Human NTSR1 full length protein-synthetic nanodisc
Human NTSR1 full length protein-synthetic nanodisc
PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag NTSR1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with NTSR1-Nanodisc is 2.583ng/ml.
Figure2. Human NTSR1-Nanodisc, Flag Tag on SDS-PAGE