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Dima Biotech

SKU(재고 관리 코드):FLP100138

Human CB2 full length protein-synthetic nanodisc

Human CB2 full length protein-synthetic nanodisc

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통합 견적 요청
Size
PRODUCT DATA
TARGET

SYNONYMS

CB-2; CNR2; CX5

DESCRIPTION

Human CB2 full length protein-synthetic nanodisc

DELIVERY

In Stock

UNIPROT ID

P34972

EXPRESSION HOST

HEK293

PROTEIN FAMILIES

Druggable Genome, GPCR, Transmembrane

PROTEIN PATHWAYS

Neuroactive ligand-receptor interaction

MOLECULAR WEIGHT

The human full length CB2 protein has a MW of 39.7 kDa

FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

USAGE

Research use only

IMAGES

elisa-FLP100138 CB2 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag CB2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CB2-Nanodisc is 1.557ng/ml.
page-FLP100138 CB2 Fig.2 SDS PAGE 1
Figure2. Human CB2-Nanodisc, Flag Tag on SDS-PAGE

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