anti- smooth muscle actin specific antibody

anti- smooth muscle actin specific antibody

Product Name

smooth muscle actin specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ACTA2, also named as a-SMA,AAT6;ACTSA belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6(AAT6). The immunogen of this antibody is a specific domain of ACTA2. This antibody stains the aorta only.

IMMUNOGEN INFORMATION

Immunogen

actin, alpha 2, smooth muscle, aorta

Synonyms

a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 Smooth muscle Actin Specific, Actin, aortic smooth muscle, Alpha actin 2, Alpha SMA, Alpha SMA Specific, a-SMA, smooth muscle actin, α SMA

Observed MW

42 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P62736

IMAGES

Immunohistochemistry of paraffin-embedded human heart using FNab08038(ACTA2-Specific antibody) at dilution of 1:1000

Immunofluorescent analysis of ( 4% PFA ) fixed mouse heart tissue using FNab08038 ( ACTA2 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab08038(a-SMA specific Antibody) at dilution of 1:600