anti- Integrin alpha 6 antibody

Product Name

Integrin alpha 6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia(EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia(PA-JEB) or aplasia cutis congenita with gastrointestinal atresia.

IMMUNOGEN INFORMATION

Immunogen

integrin, alpha 6

Synonyms

ITGA6, CD49f, FLJ18737, Integrin alpha 6, ITGA6B

Observed MW

120 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P23229

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