anti- BAX antibody

Unveil the functions of BAX with our Anti-BAX Antibody. This 100µg antibody is your passport to exploring the roles of BAX, a protein involved in apoptosis and critical in cancer research.

Engineered for precision and reliability, this antibody excels in various applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an indispensable tool in your laboratory.

BAX, a pro-apoptotic protein, plays a central role in programmed cell death and has significant implications in cancer biology. With this antibody in your arsenal, you're better equipped to explore its functions. Whether you're investigating apoptotic pathways or studying its involvement in cancer progression, this antibody is your trusted research partner.

Elevate your scientific endeavors by ordering your Anti-BAX Antibody today and gain deeper insights into the dynamic world of BAX biology.

Product Name

BAX antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

IMMUNOGEN INFORMATION

Immunogen

BCL2-associated X protein

Synonyms

BCL2L4, Apoptosis regulator BAX, BAX

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q07812

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