anti- CD44 antibody

Delve into the world of cell adhesion, migration, and signaling with our Anti-CD44 Antibody, now available in a 100µg size. CD44, a multifunctional cell surface glycoprotein, is involved in numerous cellular processes, including cell adhesion, migration, lymphocyte activation, and tumor metastasis.

This monoclonal antibody offers high specificity and sensitivity, making it an invaluable tool for researchers investigating CD44-mediated functions in various biological contexts. With 100µg of this antibody, you'll have a substantial supply for multiple experiments, ensuring the uninterrupted progression of your research.

Explore the intricate mechanisms by which CD44 participates in cell adhesion, extracellular matrix interaction, and its role in cancer biology and tissue regeneration. Investigate the molecular intricacies of CD44-mediated processes, contributing to our understanding of cell adhesion dynamics and potential therapeutic interventions.

Product Name

CD44 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

IMMUNOGEN INFORMATION

Immunogen

CD44 molecule (Indian blood group)

Synonyms

LHR, MDU2, MDU3, MIC4

Observed MW

45-50 kDa, 73-81 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P16070

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