anti- DICER1 antibody

The anti-DICER1 antibody, available in a 100µg size, is an essential tool for researchers investigating DICER1, a critical enzyme involved in the biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs).

DICER1 plays a pivotal role in post-transcriptional gene regulation, making this antibody an invaluable asset for studies related to gene expression control, RNA interference, and miRNA-mediated processes. With exceptional specificity and sensitivity, this antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

Our anti-DICER1 antibody is sourced from high-quality materials and subjected to rigorous validation to ensure accurate and reproducible results. Researchers delving into the functions of DICER1 in cellular differentiation, cancer biology, or its implications in developmental disorders will find this antibody indispensable for their work.

The 100µg size provides an ample supply for multiple experiments, offering flexibility in experimental design. Whether unraveling DICER1's role in post-transcriptional silencing, epigenetic regulation, or its involvement in diseases like DICER1 syndrome, this antibody is a critical resource for your research.

Product Name

DICER1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

dicer 1, ribonuclease type III

Synonyms

DICER, HERNA, KIAA0928

Observed MW

90-100 kDa, 210-250 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

Q9UPY3

IMAGES

K-562 cells were subjected to SDS PAGE followed by western blot with FNab10456(DICER1 antibody) at dilution of 1:1000