anti- Fibronectin antibody

Uncover the mysteries of extracellular matrix proteins with our Anti-Fibronectin Antibody, available in a 100µg vial. Fibronectin is a versatile and essential component of the ECM, playing pivotal roles in cell adhesion, migration, and tissue development. This highly specific antibody empowers researchers to investigate the multifaceted functions of Fibronectin in cell biology, ECM dynamics, and related processes with precision and reliability.

Key Features:

• Exceptional Specificity: Our Anti-Fibronectin Antibody is rigorously tested to ensure it accurately targets Fibronectin, minimizing the risk of cross-reactivity.
• Versatile Applications: Ideal for a wide range of experimental techniques, including immunohistochemistry, Western blotting, and immunoprecipitation.
• Ample Quantity: With 100µg, you have a generous supply for multiple experiments.
• Top-Tier Quality: Manufactured to the highest industry standards, guaranteeing consistent and reproducible results.
• Advance Your Research: Whether you're studying cell-matrix interactions, tissue development, or adhesion mechanisms, our Anti-Fibronectin Antibody is your key to unlocking new knowledge.

Uncover the role of Fibronectin in complex biological processes and elevate your research with our Anti-Fibronectin Antibody.

Product Name

Fibronectin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)

IMMUNOGEN INFORMATION

Immunogen

fibronectin 1

Synonyms

CIG, Cold insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, Fibronectin, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF

Observed MW

220-270 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P02751

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer using FNab10458(FN1 antibody) at dilution of 1:50

U-87MG cells were subjected to SDS PAGE followed by western blot with FNab10458(FN1 antibody) at dilution of 1:1000