anti- EIF5A antibody

Investigate EIF5A (Eukaryotic Translation Initiation Factor 5A) with our Anti-EIF5A Antibody, available in a 100µg size. EIF5A is a critical factor in translation initiation, playing a pivotal role in protein synthesis and the regulation of gene expression.

This antibody is meticulously validated for specificity, ensuring its suitability for research on EIF5A's function, its interactions with translation factors, and its implications in various cellular processes. Whether your studies focus on translation initiation, ribosome assembly, or gene regulation, this antibody is an invaluable addition to your scientific toolkit.

Enhance your understanding of EIF5A and its multifaceted functions by ordering your 100µg vial today. With this antibody, you can advance your research into the intricate world of translation initiation and protein synthesis.

Product Name

EIF5A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 5A

Observed MW

17 kDa/34 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P63241

IMAGES

Immunohistochemistry of paraffin-embedded rat lung using FNab10466(EIF5A antibody) at dilution of 1:100

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10466(EIF5A antibody) at dilution of 1:1000