Anti-NCR1 antibody

Product Name

NCR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

IMMUNOGEN INFORMATION

Immunogen

Natural cytotoxicity triggering receptor 1

Synonyms

CD335, LY94, NK-p46, NKP46, NCR1

Observed MW

46 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

O76036

IMAGES

Immunohistochemistry of paraffin-embedded human skin cancer slide using FNab10472( NCR1 Antibody) at dilution of 1:200

A431 cells were subjected to SDS PAGE followed by western blot with FNab10472( NCR1 Antibody) at dilution of 1:1000