Anti-AKR1C2 antibody

Product Name

AKR1C2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

Aldo-keto reductase family 1 member C2

Synonyms

AKR1C2, AKR1C-pseudo, BABP, DD, DD-2

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P52895

IMAGES

Immunofluorescent analysis of PC-3 cells using FNab10474(AKR1C2 Antibody) at dilution of 1:50.

A549 cells were subjected to SDS PAGE followed by western blot with FNab10474(AKR1C2 Antibody) at dilution of 1:1000