anti- CD105 antibody

In the realm of immunology, deciphering the intricacies of cell surface markers is paramount. Our Anti-CD105 Antibody, available in a 100µg size, is a powerful tool for investigating CD105, also known as endoglin. CD105 is a cell membrane glycoprotein involved in angiogenesis, vascular development, and immune regulation. With its high specificity, sensitivity, and reliability, this antibody is your key to unraveling the roles and functions of CD105 in various research contexts.

Our 100µg antibody vial provides an ample supply for extensive experiments, ensuring that your research progresses smoothly without the need for frequent antibody replenishment. Whether you are utilizing flow cytometry, immunohistochemistry, or Western blotting, our Anti-CD105 Antibody is adaptable and dependable, offering consistent and robust results.

Step confidently into the world of immunology research, armed with the knowledge that our Anti-CD105 Antibody is your trusted partner in advancing your understanding of immune responses, vascular biology, and the intricacies of CD105.

Product Name

CD105 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

endoglin

Synonyms

CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1

Observed MW

75-90 kDa, 170-180 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P17813

IMAGES

mouse spleen lysates were subjected to SDS PAGE followed by western blot with FNab10759(CD105 antibody) at dilution of 1:1000