anti- Beclin 1 antibody

Shed light on the intricate process of autophagy with our Anti-Beclin 1 Antibody. This 100µg antibody is your beacon for exploring the functions of Beclin 1, a pivotal protein involved in autophagic pathways.

Engineered for precision and reliability, this antibody excels in various applications, from Western blotting to immunofluorescence. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, enabling you to advance your autophagy research with confidence.

Beclin 1, a key player in autophagy regulation, has garnered significant attention in both basic cellular research and disease studies. With this antibody in your toolkit, you're better equipped to unravel its multifaceted functions. Whether you're investigating its roles in cellular homeostasis or its implications in neurodegenerative disorders, this antibody stands as your trusted research companion.

Illuminate the path to scientific discovery by adding our Anti-Beclin 1 Antibody to your experiments today. Uncover the secrets of Beclin 1 and gain deeper insights into the dynamic world of autophagy and cell survival.

Product Name

Beclin 1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

IMMUNOGEN INFORMATION

Immunogen

beclin 1, autophagy related

Synonyms

ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:5000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q14457

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer using FNab10873(Beclin 1 antibody) at dilution of 1:100

Hela cells were subjected to SDS PAGE followed by western blot with FNab10873(Beclin 1 Antibody) at dilution of 1:3000