Uncoated Human GDNF(Glial Cell Line Derived Neurotrophic Factor) ELISA Kit

The Uncoated Human GDNF ELISA Kit is a highly sensitive and specific assay designed for the quantitative measurement of Glial Cell Line Derived Neurotrophic Factor (GDNF) in human serum, plasma, and cell culture supernatants. This kit is uncoated, meaning that the capture antibody is not pre-coated onto the microplate, allowing for greater flexibility in assay design and optimization. The kit includes all necessary reagents and materials for the assay, including a pre-coated standard curve, detection antibody, and streptavidin-HRP conjugate.

GDNF is a neurotrophic factor that plays a critical role in the development and maintenance of the nervous system. It has been implicated in a variety of neurological disorders, including Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). The Uncoated Human GDNF ELISA Kit provides a reliable and accurate method for measuring GDNF levels in biological samples, allowing researchers to better understand the role of this important protein in disease pathogenesis and potential therapeutic interventions.

The assay is performed in a standard sandwich ELISA format, with the capture antibody binding GDNF in the sample and the detection antibody detecting the bound GDNF. The streptavidin-HRP conjugate then binds to the detection antibody, allowing for the detection of GDNF via a colorimetric reaction. The kit has a detection range of 31.25-2000 pg/mL, with a sensitivity of 18.75 pg/mL. The Uncoated Human GDNF ELISA Kit is a valuable tool for researchers studying the role of GDNF in neurological disorders and for the development of potential therapeutic interventions.