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Elabscience
SKU(재고 관리 코드):E-UNEL-H0190
Uncoated Human sRANKL(Soluble Receptor Activator of Nuclear factor-kB Ligand) ELISA Kit
Uncoated Human sRANKL(Soluble Receptor Activator of Nuclear factor-kB Ligand) ELISA Kit
The Uncoated Human sRANKL ELISA Kit is a highly sensitive and specific assay designed for the quantitative measurement of soluble Receptor Activator of Nuclear factor-kB Ligand (sRANKL) in human serum, plasma, and cell culture supernatants. This kit is uncoated, meaning that the capture antibody is not pre-coated onto the microplate, allowing for greater flexibility in assay design and optimization. The kit includes all necessary reagents and components for the assay, including a pre-coated standard curve, detection antibody, and streptavidin-HRP conjugate.
The sRANKL protein is a key regulator of bone metabolism and is involved in the differentiation and activation of osteoclasts, the cells responsible for bone resorption. Dysregulation of sRANKL signaling has been implicated in a number of bone-related diseases, including osteoporosis, rheumatoid arthritis, and bone metastases. The Uncoated Human sRANKL ELISA Kit provides a reliable and accurate method for measuring sRANKL levels in biological samples, allowing for the identification of potential biomarkers and therapeutic targets for these diseases.
The assay is performed in a standard sandwich ELISA format, with the capture antibody and detection antibody binding to different epitopes on the sRANKL protein. The streptavidin-HRP conjugate then binds to the detection antibody, allowing for the detection of sRANKL levels through the addition of a chromogenic substrate. The kit has a detection range of 15.6-1000 pg/mL, with a sensitivity of 7.8 pg/mL. The Uncoated Human sRANKL ELISA Kit is a valuable tool for researchers and clinicians studying bone metabolism and related diseases, providing a reliable and accurate method for measuring sRANKL levels in biological samples.
The sRANKL protein is a key regulator of bone metabolism and is involved in the differentiation and activation of osteoclasts, the cells responsible for bone resorption. Dysregulation of sRANKL signaling has been implicated in a number of bone-related diseases, including osteoporosis, rheumatoid arthritis, and bone metastases. The Uncoated Human sRANKL ELISA Kit provides a reliable and accurate method for measuring sRANKL levels in biological samples, allowing for the identification of potential biomarkers and therapeutic targets for these diseases.
The assay is performed in a standard sandwich ELISA format, with the capture antibody and detection antibody binding to different epitopes on the sRANKL protein. The streptavidin-HRP conjugate then binds to the detection antibody, allowing for the detection of sRANKL levels through the addition of a chromogenic substrate. The kit has a detection range of 15.6-1000 pg/mL, with a sensitivity of 7.8 pg/mL. The Uncoated Human sRANKL ELISA Kit is a valuable tool for researchers and clinicians studying bone metabolism and related diseases, providing a reliable and accurate method for measuring sRANKL levels in biological samples.
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