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SKU(재고 관리 코드):LMB710Hu

Magnetic Luminex Assay Kit for Glycocalicin (GC) ,etc.

Magnetic Luminex Assay Kit for Glycocalicin (GC) ,etc.

Detection range
Size
Sensitivity

Product No.

LMB710Hu

Organism Species

Homo sapiens (Human).

Sample Type

Plasma

Test Method

Double-antibody Sandwich

Assay Length

3.5h

Detection Range

0.98-1000pg/mL

Sensitivity

The minimum detectable dose of this kit is typically less than 0.327 pg/mL.

UOM

1Plex 2Plex 3Plex 4Plex 5Plex 6Plex 7Plex 8Plex.

 

Specificity

This assay has high sensitivity and excellent specificity for detection of Glycocalicin (GC) ,etc..
No significant cross-reactivity or interference between Glycocalicin (GC) ,etc. and analogues was observed.

Recovery

Matrices listed below were spiked with certain level of recombinant Glycocalicin (GC) ,etc. and the recovery rates were calculated by comparing the measured value to the expected amount of Glycocalicin (GC) ,etc. in samples.

Matrix Recovery range (%) Average(%)
serum(n=5) 79-94 85
EDTA plasma(n=5) 78-93 85
heparin plasma(n=5) 80-103 89

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Glycocalicin (GC) ,etc. were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Glycocalicin (GC) ,etc. were tested on 3 different plates, 8 replicates in each plate.
CV(%) = SD/meanX100
Intra-Assay: CV<10%
Inter-Assay: CV<12%

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Glycocalicin (GC) ,etc. and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample 1:2 1:4 1:8 1:16
serum(n=5) 96-105% 95-103% 93-101% 84-96%
EDTA plasma(n=5) 83-96% 90-98% 78-92% 78-90%
heparin plasma(n=5) 84-97% 94-101% 86-96% 86-93%

Stability

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Reagents and materials provided

Reagents Quantity Reagents Quantity
96-well plate 1 Plate sealer for 96 wells 4
Pre-Mixed Standard 2 Standard Diluent 1×20mL
Pre-Mixed Magnetic beads (22#:GC) 1 Analysis buffer 1×20mL
Pre-Mixed Detection Reagent A 1×120μL Assay Diluent A 1×12mL
Detection Reagent B (PE-SA) 1×120μL Assay Diluent B 1×12mL
Sheath Fluid 1×10mL Wash Buffer (30 × concentrate) 1×20mL
Instruction manual 1

Assay procedure summary

1. Preparation of standards, reagents and samples before the experiment;
2. Add 100μL standard or sample to each well,
    add 10μL magnetic beads, and incubate 90min at 37°C on shaker;
3. Remove liquid on magnetic frame, add 100μL prepared Detection Reagent A. Incubate 60min at 37°C on shaker;
4. Wash plate on magnetic frame for three times;
5. Add 100μL prepared Detection Reagent B, and incubate 30 min at 37°C on shaker;
6. Wash plate on magnetic frame for three times;
7. Add 100μL sheath solution, swirl for 2 minutes, read on the machine.

 

Magazine Citations
Nanoscale. A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets Pubmed:Pmc4300948
Thrombosis Research Factors associated with the platelet count in patients with chronic hepatitis C Pubmed:25728497
Proteomics Clinical Applications iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism Pubmed:29274201
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB710Hu01 Recombinant Glycocalicin (GC) Positive Control; Immunogen; SDS-PAGE; WB.
PAB710Hu01 Polyclonal Antibody to Glycocalicin (GC) WB; IHC; ICC; IP.
LAB710Hu71 Biotin-Linked Polyclonal Antibody to Glycocalicin (GC) WB; IHC; ICC.
SEB710Hu ELISA Kit for Glycocalicin (GC) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB710Hu Magnetic Luminex Assay Kit for Glycocalicin (GC) ,etc. Magnetic Luminex Assay for Antigen Detection.
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