NFκB-p105(Phospho Ser927) Polyclonal Antibody

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

The NFκB-p105(Phospho Ser927) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphorylated Serine 927 on the NFκB-p105 protein. This antibody is produced using high-quality polyclonal antibodies that have been rigorously tested for specificity and sensitivity. The NFκB-p105(Phospho Ser927) Polyclonal Antibody is ideal for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody is suitable for use in both research and diagnostic applications and is available in a range of sizes to meet your specific needs. With its high specificity and sensitivity, the NFκB-p105(Phospho Ser927) Polyclonal Antibody is an essential tool for any researcher or clinician working in the field of NFκB signaling.