NFκB-p65(Phospho Thr435) Polyclonal Antibody

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor| NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL| RELA| or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA. Four transcript variants encoding different isoforms have been found for this gene.

The NFκB-p65(Phospho Thr435) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated NFκB-p65 at Thr435 residue. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

NFκB-p65 is a crucial transcription factor involved in various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of NFκB-p65 at Thr435 has been shown to play a critical role in the regulation of its activity and downstream signaling pathways.

The NFκB-p65(Phospho Thr435) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of NFκB-p65 at Thr435, enabling accurate and precise detection in various experimental settings. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence applications.

With its high sensitivity and specificity, this antibody offers researchers a valuable tool for studying the phosphorylation status and functional implications of NFκB-p65 in diverse biological systems. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

The NFκB-p65(Phospho Thr435) Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is available in various sizes to accommodate different experimental needs.

In summary, the NFκB-p65(Phospho Thr435) Polyclonal Antibody is a top-quality research reagent that provides accurate and reliable detection of phosphorylated NFκB-p65 at Thr435. Its exceptional specificity, sensitivity, and versatility make it an indispensable tool for scientists investigating the role of NFκB-p65 in various biological processes.