NFATc4(Phospho Ser168/S170) Polyclonal Antibody

This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

The NFATc4(Phospho Ser168/S170) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NFATc4 protein phosphorylation at Serine 168 and Serine 170 residues. This antibody is produced using advanced immunization techniques, resulting in a high affinity and specificity towards the phosphorylated form of NFATc4.

NFATc4 is a transcription factor that plays a crucial role in the regulation of gene expression in various cellular processes, including immune response, development, and differentiation. Phosphorylation of NFATc4 at Serine 168 and Serine 170 residues is known to be a key event in its activation and nuclear translocation, leading to the initiation of downstream gene transcription.

The NFATc4(Phospho Ser168/S170) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated NFATc4 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for use in a wide range of species, including human, mouse, and rat, making it a versatile tool for researchers working in diverse fields of study.

In summary, the NFATc4(Phospho Ser168/S170) Polyclonal Antibody is a highly reliable and specific reagent that enables the detection and analysis of NFATc4 protein phosphorylation at Serine 168 and Serine 170 residues. Its exceptional performance and versatility make it an invaluable tool for researchers investigating the role of NFATc4 in various biological processes.