NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.

The NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NFKappaB-p65 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the acetylated form of lysine 218 on the NFKappaB-p65 protein.

The NFKappaB-p65 protein plays a crucial role in the regulation of numerous cellular processes, including inflammation, immune response, and cell survival. The acetylation of lysine 218 on NFKappaB-p65 has been shown to modulate its transcriptional activity, making it an important target for research in the field of cellular signaling and gene expression.

This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of NFKappaB-p65 protein in complex biological samples.

The NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy integration into existing laboratory protocols.

With its exceptional performance and reliability, the NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody is an indispensable tool for researchers studying the intricate mechanisms of cellular signaling and gene regulation.