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ELK Biotechnology
SKU(재고 관리 코드):ES10386
NFX1 Rabbit Polyclonal Antibody
NFX1 Rabbit Polyclonal Antibody
NFX1 Rabbit Polyclonal Antibody
Overview
| Product name: | NFX1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 80-160 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 123kD |
| GeneID（Human）: | 4799 |
| Human Swiss-Prot No: | Q12986 |
| Cellular localization: | Nucleus. |
| Background: | MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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