NISCH Rabbit Polyclonal Antibody

This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans| this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue| this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor.

The NISCH Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of NISCH protein expression in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure exceptional performance and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

The NISCH Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards the NISCH protein, enabling precise and sensitive detection even at low expression levels. Its robust and consistent performance guarantees reliable and reproducible results, making it an ideal choice for both research and diagnostic purposes.

This antibody has been extensively tested on a wide range of tissues and cell lines, demonstrating its versatility and suitability for various experimental settings. Its exceptional specificity ensures minimal cross-reactivity with other proteins, thereby minimizing false-positive results and enhancing the reliability of your data.

The NISCH Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its optimized formulation ensures long-term stability and consistent performance, allowing for multiple experiments without compromising the quality of results.

With its exceptional sensitivity, specificity, and reliability, the NISCH Rabbit Polyclonal Antibody is an indispensable tool for researchers and clinicians seeking to unravel the intricate mechanisms underlying NISCH protein function and its potential implications in various physiological and pathological processes.

The NISCH Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NISCH protein expression in various biological samples. This antibody is produced using a rabbit host, ensuring superior sensitivity and affinity towards the target protein.

With its exceptional performance, the NISCH Rabbit Polyclonal Antibody offers researchers a valuable resource for investigating the role of NISCH in cellular processes and disease mechanisms. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NISCH Rabbit Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, ensuring accurate and precise results. Its high specificity enables researchers to confidently study NISCH protein expression in complex biological systems.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The NISCH Rabbit Polyclonal Antibody is available in different sizes to accommodate various experimental needs.

In summary, the NISCH Rabbit Polyclonal Antibody is a reliable and specific tool for the detection and analysis of NISCH protein expression. Its high sensitivity, specificity, and ease of use make it an ideal choice for researchers studying the role of NISCH in various biological processes.