NPL4 Polyclonal Antibody

Binds ubiquitinated proteins via its RanBP2-type zinc finger.,The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway:Protein degradation; proteasomal ubiquitin-dependent pathway.,Belongs to the NPL4 family.,Contains 1 RanBP2-type zinc finger.,subcellular location:Associated with the endoplasmic reticulum and nuclear.,subunit:Heterodimer with UFD1L. The heterodimer binds ubiquitinated proteins. The heterodimer binds to VCP and inhibits Golgi membrane fusion.,tissue specificity:Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver.,

The NPL4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NPL4 protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NPL4 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing accurate and reliable results. This antibody is derived from rabbit serum, providing a robust and consistent source of high-quality antibodies.

With its excellent performance characteristics, the NPL4 Polyclonal Antibody offers researchers a valuable tool for studying the role of NPL4 in various cellular processes. Its ability to specifically recognize and bind to NPL4 protein enables precise and reliable quantification, facilitating in-depth investigations into the function and regulation of this protein.

The NPL4 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution steps. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and reducing the need for frequent reordering.

In summary, the NPL4 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of NPL4 protein expression. Its exceptional sensitivity, specificity, and ease of use make it an invaluable asset for researchers studying the role of NPL4 in various biological processes.