NR0B2 Polyclonal Antibody

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.

The NR0B2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of NR0B2 protein expression in various biological samples. This antibody has been extensively validated for its exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The NR0B2 Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence, demonstrating its versatility and reliability.

With its excellent performance characteristics, the NR0B2 Polyclonal Antibody is an ideal choice for researchers and scientists working in the fields of molecular biology, biochemistry, and cell biology. Its ability to specifically recognize NR0B2 protein enables the investigation of its role in various physiological and pathological processes.

This antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into experimental workflows. It is provided in a liquid formulation, ensuring ease of handling and minimizing the risk of sample contamination.

In summary, the NR0B2 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of NR0B2 protein expression. Its exceptional performance characteristics make it an invaluable asset for researchers seeking to unravel the complexities of NR0B2 biology.