• Western blot testing of lysate from human HeLa cells treated with Trichostatin A, with acetyl-Histone H2A Antibody (Lys9). Predicted molecular weight ~14 kDa.
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NSJ Bioreagents

RQ5085

Acetyl-Histone H2A Antibody (Lys9)

Acetyl-Histone H2A Antibody (Lys9)

Size

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]

Specifications

Family Primary antibody
Formulation Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Format Purified
Clone DEB-8
Host Animal Rabbit
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Species Reactivity Human, Mouse
Application IHC-P, WB
Application Details Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:500-1:1000
Application Note Optimal dilution of the acetyl-Histone H2A Antibody (Lys9) should be determined by the researcher.
Localization Nuclear
Immunogen A synthetic peptide specific to human Histone H2A (surrounding acetylated lysine 9) was used as the immunogen for the Histone H2A antibody.
Purity Affinity purified
Storage Store the acetyl-Histone H2A Antibody (Lys9) at -20oC.
Limitation This acetyl-Histone H2A Antibody (Lys9) is available for research use only.
Uniprot # P04908
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/acetyl-histone-h2a-antibody-lys9-deb-8-rq5085
Title Acetyl-Histone H2A Antibody (Lys9)
Description Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]
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