• Western blot testing of human CEM cell lysate with ATF7IP2 antibody. Predicted molecular weight ~76 kDa.
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NSJ Bioreagents

F54547-0.08ML

ATF7IP2 Antibody / MCAF2

ATF7IP2 Antibody / MCAF2

Size

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human, Mouse
Application FACS, IHC-P, WB
Application Details Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
Application Note The stated application concentrations are suggested starting points. Titration of the ATF7IP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Nuclear
Immunogen A portion of amino acids 318-347 from the human protein was used as the immunogen for the ATF7IP2 antibody .
Purity Antigen affinity purified
Storage Aliquot the ATF7IP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This ATF7IP2 antibody is available for research use only.
Uniprot # Q5U623
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/atf7ip2-antibody-mcaf2-f54547
Title ATF7IP2 Antibody / MCAF2
Description Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
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