• CCR7 antibody western blot analysis in 293 (lane 1), Ramos (2), MDA-MB231 (3) cell line and mouse spleen tissue (4) lysate. Predicted size ~45 kDa
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NSJ Bioreagents

F48967-0.08ML

CCR7 Antibody

CCR7 Antibody

Size

CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human, Mouse
Application WB, IHC, IF, FACS, ELISA
Application Details Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
Application Note Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.
Purity Antigen affinity
Storage Aliquot the CCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This CCR7 antibody is available for research use only.
Uniprot # P32248
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/ccr7-antibody-f48967
Title CCR7 Antibody
Description CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
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