• IHC staining of FFPE human breast cancer tissue with CFD antibody. Required HIER: steam section in pH8 EDTA buffer for 20 min and allow to cool prior to testing.
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NSJ Bioreagents

RQ4073

CFD Antibody / Complement Factor D

CFD Antibody / Complement Factor D

Size

Factor D is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, IHC-P, ELISA
Application Details Western Blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the CFD antibody should be determined by the researcher.
Localization Secreted
Immunogen A recombinant human partial protein corresponding to amino acids I26-A253 was used as the immunogen for the CFD antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the CFD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This CFD antibody is available for research use only.
Uniprot # P00746
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cfd-antibody-complement-factor-d-rq4073
Title CFD Antibody / Complement Factor D
Description Factor D is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
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