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NSJ Bioreagents
SKU(재고 관리 코드):F52012-0.08ML
CFP Antibody / Complement Factor P / Properdin
CFP Antibody / Complement Factor P / Properdin
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, FACS, ELISA |
| Application Details | Western blot: 1:1000,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the CFP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CFP antibody is available for research use only. |
| Uniprot # | P27918 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cfp-antibody-complement-factor-p-properdin-f52012 |
| Title | CFP Antibody / Complement Factor P / Properdin |
| Description | This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. |
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