• Phospho-c-Myc Antibody (pT58), 0.4ml
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NSJ Bioreagents

F48482-0.4ML

Phospho-c-Myc Antibody (pT58), 0.4ml

Phospho-c-Myc Antibody (pT58), 0.4ml

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c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

Specifications

Catalog No F48482-0.4ML
Family Primary antibody
Qty 0.4ml
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Predicted Species Reactivity Bovine,Chicken,Mouse,Pig,Rat,Xenopus,Zebrafish
Application DB, WB, ELISA
Application Details Dot blot: 1:500,Western blot: 1:1000
Application Note Titration of the phospho c-Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Status Available
PDF Link Product Data Sheet (PDF)
Limitation This phospho c-Myc antibody is available for research use only.
Uniprot # P01106
Purity Antigen affinity
Immunogen This phospho c-Myc antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT58 of human MYC.
Storage Aliquot the phospho c-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Title Phospho-c-Myc Antibody (pT58)
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