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NSJ Bioreagents
SKU(재고 관리 코드):F49548-0.4ML
mTOR Antibody, 0.4ml
mTOR Antibody, 0.4ml
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FRAP1/mTOR belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. It is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Specifications
| Catalog No | F49548-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Mouse,Rat |
| Application | WB, IHC, IF, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Note | Titration of the mTOR antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This mTOR antibody is available for research use only. |
| Uniprot # | P42345 |
| Purity | Antigen affinity |
| Immunogen | A portion of amino acids 2459-2488 from the human protein was used as the immunogen for this mTOR antibody. |
| Storage | Aliquot the mTOR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | mTOR Antibody |
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