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    NSJ Bioreagents

    V3691-20UG

    Cadherin 16 Antibody, 20 ug

    Cadherin 16 Antibody, 20 ug

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    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin / Cadherin 16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.

    Specifications

    Catalog No V3691-20UG
    Family Primary antibody
    Qty 20 ug
    Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
    Format Purified
    Clone CDH16/2125
    Host Animal Mouse
    Clonality Monoclonal (mouse origin)
    Isotype Mouse IgG1, kappa
    Species Reactivity Human
    Application ELISA, WB, IHC-P
    Application Details ELISA: order BSA/sodium azide-free format for coating,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
    Application Note Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.<br><br>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
    Status Available
    PDF Link Product Data Sheet (PDF)
    Limitation This Cadherin 16 antibody is available for research use only.
    Uniprot # O75309
    Purity Protein G affinity chromatography
    Immunogen Recombinant human partial protein (within amino acids 371-507) was used as the immunogen for the Cadherin 16 antibody.
    Storage Store the Cadherin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
    Localization Cell surface with some cytoplasmic
    Title Cadherin 16 Antibody
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