NCAM / CD56 Antibody, 100ug

Neural cell adhesion molecule 1 (NCAM1) is a cell surface glycoprotein encoded by the NCAM1 gene and is widely recognized as the cluster of differentiation antigen CD56. CD56 Antibody for IHC / NCAM1 IHC Antibody (clone MSVA-056R) targets this well-characterized membrane protein and is designed for immunohistochemistry analysis of NCAM1 expression in tissue samples. NCAM1 belongs to the immunoglobulin superfamily of cell adhesion molecules and functions in cell-cell interactions, neuronal development, and immune cell signaling.<br><br>NCAM1 antibody, also referred to as CD56 antibody or Neural cell adhesion molecule antibody in the literature, detects a transmembrane adhesion protein expressed on multiple cell types including neurons, neuroendocrine cells, skeletal muscle, and subsets of immune cells. CD56 is particularly well known as a marker of natural killer cells and certain activated T cell populations. Because of its consistent surface expression in these cell types, CD56 antibody staining is frequently used in studies examining immune cell populations and neuroendocrine differentiation.<br><br>In tissue sections, NCAM1 is typically localized to the cell membrane where it mediates homophilic and heterophilic interactions that regulate cell adhesion and migration. The protein contributes to neuronal growth and synaptic plasticity within the nervous system, while also participating in immune cell communication and migration. Expression of NCAM1 has also been documented in a variety of epithelial and neuroendocrine tissues, reflecting its broader roles in tissue organization and cellular signaling.<br><br>CD56 expression is widely studied in oncology because many tumor types exhibit characteristic patterns of NCAM1 expression. Neuroendocrine tumors, small cell carcinomas, and certain hematologic malignancies frequently demonstrate strong CD56 staining patterns, making NCAM1 antibody detection valuable for research examining tumor biology and cellular differentiation. In addition, CD56 antibody staining is often used in studies investigating immune infiltration and natural killer cell distribution within tissues.<br><br>CD56 Antibody for IHC / NCAM1 IHC Antibody (clone MSVA-056R) enables detection of Neural cell adhesion molecule / NCAM1 expression in formalin-fixed paraffin-embedded tissues. Analysis of CD56 staining patterns can help researchers investigate cellular adhesion mechanisms, neuroendocrine differentiation, and immune cell populations within complex tissue environments.<br><br>This antibody is also part of a broader collection of <a href='/ihc-antibodies-tissue-microarray-validated.html'>IHC antibodies validated by tissue microarray analysis</a>, supporting consistent staining across normal and cancer tissues.

Specifications