Nur77(Phospho Ser351) Polyclonal Antibody

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

The Nur77(Phospho Ser351) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Nur77 protein phosphorylated at Ser351. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

The Nur77 protein, also known as NR4A1, is a member of the nuclear receptor superfamily and plays a crucial role in various cellular processes, including apoptosis, inflammation, and metabolism. Phosphorylation of Nur77 at Ser351 has been implicated in the regulation of its transcriptional activity and protein stability. Therefore, the ability to detect and measure the phosphorylation status of Nur77 at Ser351 is of great importance in understanding its functional role in different biological contexts.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

The Nur77(Phospho Ser351) Polyclonal Antibody is supplied as a liquid formulation, ready to use for various applications in molecular biology and biomedical research. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and reliability, the Nur77(Phospho Ser351) Polyclonal Antibody is an indispensable tool for researchers studying the role of Nur77 in cellular signaling pathways and disease mechanisms.