ODC Polyclonal Antibody

SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.

The ODC Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of ornithine decarboxylase (ODC) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ODC protein. The resulting polyclonal antibody exhibits high affinity and specificity towards ODC protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The ODC Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a column containing immobilized ODC protein. This ensures that the antibody is highly specific and free from any non-specific binding. The antibody is also provided in a liquid format, which makes it easy to use and eliminates the need for reconstitution.

The ODC Polyclonal Antibody has been extensively validated for its performance in various applications. It has been shown to detect ODC protein in a wide range of species, including human, mouse, rat, and bovine. The antibody has also been shown to be highly sensitive, with a detection limit of as low as 0.1 ng/mL.

In summary, the ODC Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of ODC protein in various biological samples. Its high affinity and specificity make it an essential tool for researchers studying the role of ODC in various physiological and pathological processes.