p107(Phospho Thr369) Polyclonal Antibody

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation| as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen| with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition| both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein| it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms hav

The p107(Phospho Thr369) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of p107 protein phosphorylated at threonine 369. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The p107 protein plays a crucial role in cell cycle regulation and is known to be phosphorylated at multiple sites, including threonine 369. Phosphorylation of p107 at this specific site has been implicated in various cellular processes, such as cell proliferation, differentiation, and apoptosis. Therefore, the ability to accurately detect and quantify p107 phosphorylation at threonine 369 is of great importance in understanding the underlying mechanisms of these processes.

The p107(Phospho Thr369) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of p107 phosphorylation at threonine 369. It has been extensively validated through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. This antibody demonstrates minimal cross-reactivity with non-phosphorylated p107 and other related proteins, ensuring reliable and accurate results.

Furthermore, the p107(Phospho Thr369) Polyclonal Antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and high reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The antibody is also provided in a convenient format, allowing for easy storage and long-term stability.

In summary, the p107(Phospho Thr369) Polyclonal Antibody is a valuable tool for researchers studying p107 protein phosphorylation at threonine 369. Its exceptional specificity, sensitivity, and reliability make it an ideal choice for various applications, including Western blotting, immunoprecipitation, and immunofluorescence. With this antibody, researchers can gain valuable insights into the role of p107 phosphorylation in cellular processes, advancing our understanding of fundamental biological mechanisms.