p70 S6 Kinase alpha(Phospho Thr229) Polyclonal Antibody

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

The p70 S6 Kinase alpha(Phospho Thr229) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of p70 S6 Kinase alpha protein phosphorylated at Thr229. This antibody has been rigorously validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The p70 S6 Kinase alpha is a serine/threonine kinase that plays a crucial role in the regulation of cell growth and proliferation. It is a downstream effector of the mammalian target of rapamycin (mTOR) signaling pathway and is involved in the translation of mRNA into proteins. Phosphorylation of p70 S6 Kinase alpha at Thr229 is an important post-translational modification that regulates its activity and function.

This polyclonal antibody has been raised against a synthetic peptide corresponding to the phosphorylated Thr229 region of p70 S6 Kinase alpha. It exhibits high affinity and specificity towards the phosphorylated form of p70 S6 Kinase alpha, enabling accurate and reliable detection of this protein in various biological samples.

The p70 S6 Kinase alpha(Phospho Thr229) Polyclonal Antibody is supplied as a liquid formulation in a convenient size of 100 µg. It has been purified using protein A affinity chromatography and is provided in a phosphate-buffered saline (PBS) solution containing 0.02% sodium azide as a preservative.

This antibody is suitable for use in both research and diagnostic applications. It can be used to investigate the role of p70 S6 Kinase alpha in various cellular processes, such as cell growth, proliferation, and differentiation. Additionally, it can be utilized to study the dysregulation of p70 S6 Kinase alpha in various diseases, including cancer and metabolic disorders.

In summary, the p70 S6 Kinase alpha(Phospho Thr229) Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of phosphorylated p70 S6 Kinase alpha protein. Its high specificity, sensitivity, and validated performance make it an essential reagent for researchers and clinicians working in the field of cell signaling and protein phosphorylation.