p70 S6 Kinase alpha(Phospho Thr421) Polyclonal Antibody

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

The p70 S6 Kinase alpha(Phospho Thr421) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of p70 S6 Kinase alpha protein phosphorylated at Thr421. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The p70 S6 Kinase alpha is a serine/threonine kinase that plays a crucial role in the regulation of cell growth and proliferation. It is a downstream effector of the mammalian target of rapamycin (mTOR) signaling pathway and is involved in the translation of mRNA into proteins. Phosphorylation of p70 S6 Kinase alpha at Thr421 is a key event in its activation and subsequent downstream signaling.

This polyclonal antibody has been developed using high-quality immunogens and advanced immunization techniques, ensuring its specificity and sensitivity. It has been extensively tested and validated to provide reliable and reproducible results. The antibody exhibits minimal cross-reactivity with other related proteins, ensuring accurate detection and quantification of p70 S6 Kinase alpha phosphorylated at Thr421.

The p70 S6 Kinase alpha(Phospho Thr421) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is suitable for use in various experimental settings, including basic research, drug discovery, and clinical diagnostics.

In summary, the p70 S6 Kinase alpha(Phospho Thr421) Polyclonal Antibody is a reliable and versatile tool for the study of p70 S6 Kinase alpha phosphorylation at Thr421. Its high specificity, sensitivity, and reproducibility make it an essential reagent for researchers and scientists working in the field of cell signaling and protein translation.