PAK alpha(Phospho Ser199) Polyclonal Antibody

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The PAK alpha (Phospho Ser199) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of PAK alpha protein phosphorylated at Ser199. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

PAK alpha, also known as p21-activated kinase alpha, is a serine/threonine protein kinase that plays a crucial role in various cellular processes, such as cell proliferation, migration, and cytoskeletal reorganization. Phosphorylation of PAK alpha at Ser199 has been implicated in the regulation of its activity and downstream signaling pathways.

The PAK alpha (Phospho Ser199) Polyclonal Antibody has been developed using high-quality materials and advanced techniques to ensure optimal performance and reliability. It exhibits excellent specificity, showing minimal cross-reactivity with other related proteins. Furthermore, it demonstrates high sensitivity, allowing for the detection of low levels of phosphorylated PAK alpha.

This antibody is supplied as a liquid formulation, making it easy to handle and use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The PAK alpha (Phospho Ser199) Polyclonal Antibody is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the PAK alpha (Phospho Ser199) Polyclonal Antibody is a reliable and versatile tool for the study of PAK alpha phosphorylation at Ser199. Its high specificity, sensitivity, and compatibility with different applications make it an essential reagent for researchers investigating the role of PAK alpha in cellular processes and signaling pathways.