Pan glycine myristoylation Polyclonal Antibody

Pan3 (PAB-dependent poly(A)-specific ribonuclease subunit 3) is a 741 amino acid cytoplasmic protein belonging to the protein kinase superfamily. Containing a protein kinase domain, Pan3 is a component of the Pan nuclease complex and recruits polyadenylate-binding protein, which in turn stimulates Pan2 nuclease activity. It is suggested that Pan3 may have a functional role in cytoplasmic mRNA decay. Pan3 exists as three isoforms produced by alternative splicing and the gene encoding Pan3 is located on human chromosome 13. Chromosome 13 houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

The Pan glycine myristoylation Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of proteins that undergo myristoylation, a post-translational modification involving the addition of a myristoyl group to the N-terminal glycine residue. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards myristoylated proteins.

With its polyclonal nature, this antibody recognizes a wide range of myristoylated proteins, making it an ideal choice for researchers studying various cellular processes and signaling pathways. It has been extensively validated for use in Western blotting, immunoprecipitation, and immunofluorescence assays, ensuring reliable and reproducible results.

The Pan glycine myristoylation Polyclonal Antibody is manufactured under stringent quality control measures to guarantee batch-to-batch consistency and optimal performance. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody conjugation procedures.

This antibody is compatible with a variety of sample types, including cell lysates, tissue extracts, and purified proteins, enabling its application in diverse experimental settings. Its exceptional sensitivity allows for the detection of low-abundance myristoylated proteins, facilitating the exploration of their roles in cellular processes and disease mechanisms.

In summary, the Pan glycine myristoylation Polyclonal Antibody is a reliable and versatile tool for the detection and analysis of myristoylated proteins. Its high specificity, sensitivity, and ease of use make it an invaluable asset for researchers in the fields of biochemistry, cell biology, and molecular biology.