PARP-2 Polyclonal Antibody

PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

The PARP-2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Poly(ADP-ribose) polymerase 2 (PARP-2) protein. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards PARP-2.

PARP-2 is a crucial enzyme involved in DNA repair and maintenance of genomic stability. It plays a significant role in various cellular processes, including DNA damage response, cell cycle regulation, and apoptosis. The PARP-2 Polyclonal Antibody is an invaluable resource for researchers and scientists studying these fundamental biological mechanisms.

This antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and minimal cross-reactivity with other PARP family members. The PARP-2 Polyclonal Antibody guarantees accurate and reliable results, enabling precise analysis of PARP-2 expression and localization in various cell types and tissues.

With its superior quality and performance, the PARP-2 Polyclonal Antibody is an indispensable tool for researchers in the fields of molecular biology, genetics, and cancer research. Its application extends to the investigation of PARP-2 involvement in disease pathogenesis and the development of potential therapeutic strategies targeting PARP-2.

Choose the PARP-2 Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new insights into the intricate mechanisms of PARP-2-mediated cellular processes.