PARP1 Polyclonal Antibody

PARP1 Polyclonal Antibody

Introducing the PARP1 Polyclonal Antibody, a highly specific and reliable tool for the detection of Poly(ADP-ribose) polymerase 1 (PARP1) in various applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PARP1 protein, and has been extensively validated for its specificity and sensitivity.

PARP1 is a nuclear enzyme that plays a crucial role in DNA repair, chromatin remodeling, and cell death pathways. Dysregulation of PARP1 activity has been implicated in various diseases, including cancer, neurodegeneration, and inflammation. Therefore, accurate detection of PARP1 expression and localization is essential for understanding its biological functions and developing therapeutic strategies.

The PARP1 Polyclonal Antibody is suitable for use in Western blotting, immunohistochemistry, immunofluorescence, and other techniques. It recognizes both the full-length and cleaved forms of PARP1, and shows minimal cross-reactivity with other PARP family members. The antibody is provided as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the PARP1 Polyclonal Antibody is a high-quality reagent that enables accurate and specific detection of PARP1 in various experimental settings. Its superior performance and reliability make it an ideal choice for researchers and clinicians studying PARP1 biology and related diseases.