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ELK Biotechnology
SKU(재고 관리 코드):ES11259
PAX3 Rabbit Polyclonal Antibody
PAX3 Rabbit Polyclonal Antibody
PAX3 Rabbit Polyclonal Antibody
Overview
| Product name: | PAX3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 150-230 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 52kD |
| GeneID（Human）: | 5077 |
| Human Swiss-Prot No: | P23760 |
| Cellular localization: | Nucleus . |
| Background: | This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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